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AAccording to the National Institute of Diabetes and Digestive and Kidney DiseasesNIDDKover timehypertensionhigh blood pressurecan damage the kidneys and lead to chronic kidney diseaseStudies have shown that two classes of antihypertensive medications have demonstrated a protective effect on the kidneysangiotensin-converting enzymeACEinhibitorssuch as enalaprilVasotecand angiotensin II receptor blockersARBsThese studies have shown that these two classes of medications can decrease proteinurialoss of protein in the urineand can slow the progression of kidney damagebut do not reverse itEnalapril is an ACE inhibitor indicated for the treatment of hypertensioncongestive heart failurekidney problems associated with diabetesand to improve survival after a heart attackSome of the common side effects associated with enalapril treatment include coughloss of appetiteloss of tastedizzinessheadachedrowsinessinsomniadifficulty sleepingdry mouthnauseavomitingdiarrhea or mild skin itching or rashIf you experience anything unusual or bothersome while taking enalaprilit is important to contact your physicianEnalapril should be taken with a full glass of water and can be taken with or without foodWhile being treated with enalapril it is important to have your blood pressurekidney and liver function routinely monitored by your health care providerMetoprolol is also an antihypertensive medication categorized as a beta-blockerMetoprolol is indicated for the treatment of hypertensionanginachest painand for the treatment or prevention of a heart attackMetoprolol does not slow the progression of kidney damage like enalapril doesSome of the possible side effects associated with metoprolol treatment include dry mouthheartburnvomitingdiarrheaconstipationheadachedrowsinesstired feelinginsomniaanxietynervousnessdecreased sex driveimpotence or difficulty having an orgasmBeth IsaacPharmD.

QI am taking metoprorol tartrate 25 mgI was taking two in the morningand it was changed to one in the morning and one in the eveningI had a little chest pain getting adjusted to itbut now I am okayDo you think I should take Toprol XLwould that be better for me?

QI had my mitral and aortic valves replaced and have been on Metoprolol ever sinceMy heart rate is real lowCould this have anything to do with the medications?

QI have an apparent drug reactionvery bad rashand my doctor thinks it is from metoprolol due to having apunchfrom my skin in two placesThe rash sometimes itchesbut mostly just look horribleCould the metoprolol be causing the skin rashShe has had me discontinue the drug and I am taking an oral steroid for about three weeksI just began taking it.

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